NIYO & CO

Vitamin B3 derivative

Niacinamide

A versatile, generally well-tolerated multitasking ingredient.

Abstract molecular graphic representing Niacinamide (Vitamin B3 derivative)
Informational only, not medical advice. This page does not diagnose or treat any condition. See a dermatologist for guidance specific to you.

What it is

Niacinamide is a form of vitamin B3 that's become one of the most widely formulated ingredients in modern skincare, appearing in serums, moisturizers and even some cleansers. It's popular in large part because it's generally well tolerated across skin types while still being associated with a broad range of reputed benefits — texture, tone, and a more balanced look to oil production.

What it does

Niacinamide is associated with supporting the look of skin texture and tone, and is often used alongside other actives because it's typically gentle.

Who it’s for

Close to a universal ingredient — used across dry, oily, combination and sensitive skin types, and often recommended as a lower-risk way to add an 'active' to a routine that's otherwise minimal.

Possible benefits

  • Associated with a more even-looking skin tone and refined texture
  • Often included in formulas aimed at a more balanced look to visible oiliness
  • Generally considered compatible with sensitive or reactive skin
  • Layers well with most other common actives

Irritation & compatibility considerations

Niacinamide is one of the better-tolerated actives generally discussed in skincare, though a small number of people report flushing or sensitivity, particularly at higher concentrations. There's long-standing (and largely anecdotal, formulation-dependent) discussion about niacinamide and vitamin C interacting in some older formulations — modern formulations are generally considered fine to use together, but starting with one at a time is a reasonable way to isolate any reaction.

How it fits into a routine

Flexible enough for morning or night, and compatible with most other steps. It's a common 'default' serum step for people building a routine from scratch, and a common addition for people managing an oily or combination complexion.

Frequently Asked

Can niacinamide be used every day?

Yes — it's generally considered gentle enough for daily use, morning and/or night, for most skin types.

Does niacinamide help with oily skin?

It's commonly included in oil-balancing formulas and widely used for that purpose, though individual results vary and it's not a substitute for a full routine suited to oilier skin.